W van Eden Selected Research

Epitopes

2/2012	T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice.
1/2010	Cartilage proteoglycan aggrecan epitopes induce proinflammatory autoreactive T-cell responses in rheumatoid arthritis and osteoarthritis.
4/2009	Activation of nucleotide oligomerization domain 2 exacerbates a murine model of proteoglycan-induced arthritis.
1/2008	Anterior uveitis accompanies joint disease in a murine model resembling ankylosing spondylitis.
8/2000	Induction of experimental autoimmune arthritis by a public epitope of the T cell receptor variable alpha domain of an arthritogenic T cell clone.
7/2000	A self-hsp60 peptide acts as a partial agonist inducing expression of B7-2 on mycobacterial hsp60-specific T cells: a possible mechanism for inhibitory T cell regulation of adjuvant arthritis?

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W van Eden Research Topics

Disease

10	Arthritis (Polyarthritis) 07/2013 - 03/2000
8	Experimental Arthritis 07/2002 - 03/2000
5	Inflammation (Inflammations) 01/2013 - 11/2000
4	Infections 01/2016 - 09/2004
4	Autoimmune Diseases (Autoimmune Disease) 07/2013 - 08/2000
3	Rheumatoid Arthritis 01/2010 - 08/2000
3	Paratuberculosis (Johne's Disease) 03/2005 - 03/2001
2	Whooping Cough (Pertussis) 01/2016 - 09/2004
2	Hypersensitivity (Allergy) 07/2011 - 12/2000
2	Atherosclerosis 12/2007 - 10/2006
2	Asthma (Bronchial Asthma) 12/2000 - 01/2000
2	Respiratory Hypersensitivity 12/2000 - 01/2000
1	Opportunistic Infections (Opportunistic Infection) 01/2016
1	Fever (Fevers) 01/2016
1	Osteoarthritis 01/2010
1	Colitis 04/2009
1	Sacroiliitis 01/2008
1	Spondylitis 01/2008
1	Ankylosing Spondylitis 01/2008
1	Atherosclerotic Plaque (Atheroma) 10/2006
1	Diphtheria 09/2004
1	Measles 09/2004
1	Tetanus 09/2004
1	Mumps 09/2004
1	Rubella (German Measles) 09/2004
1	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 07/2003
1	Sexually Transmitted Diseases (Sexually Transmitted Disease) 07/2002
1	Multiple Sclerosis 08/2000
1	Eosinophilia 01/2000

Drug/Important Bio-Agent (IBA)

8	Peptides (Polypeptides)IBA 01/2010 - 01/2000
7	Heat-Shock Proteins (Heat-Shock Protein)IBA 07/2002 - 03/2000
6	EpitopesIBA 02/2012 - 07/2000
5	Proteoglycans (Proteoglycan)IBA 07/2013 - 01/2008
5	Proteins (Proteins, Gene)FDA Link 02/2012 - 03/2000
5	CytokinesIBA 07/2011 - 12/2000
5	Interleukin-10 (Interleukin 10)IBA 07/2003 - 03/2000
4	AntigensIBA 07/2013 - 12/2000
4	T-Cell Antigen Receptors (T-Cell Receptor)IBA 02/2012 - 08/2000
3	VaccinesIBA 01/2016 - 09/2004
3	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 07/2013 - 09/2002
2	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 01/2010 - 12/2000
2	Chaperonin 60IBA 07/2003 - 08/2000
2	Immunoglobulin G (IgG)IBA 03/2001 - 02/2001
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2016
1	Pertussis VaccineIBA 01/2016
1	tocilizumab (atlizumab)FDA Link 01/2016
1	Immunoglobulin E (IgE)IBA 01/2013
1	OvalbuminIBA 01/2013
1	AntibodiesIBA 02/2012
1	Thymic Stromal LymphopoietinIBA 07/2011
1	Interleukin-7 (Interleukin 7)IBA 07/2011
1	Neutralizing AntibodiesIBA 11/2010
1	Amino Acids FDA Link 01/2010
1	ChemokinesIBA 01/2010
1	Aggrecans (Aggrecan)IBA 01/2010
1	Acetylmuramyl-Alanyl-IsoglutamineIBA 04/2009
1	NucleotidesIBA 04/2009
1	oxidized low density lipoproteinIBA 10/2006
1	LDL Lipoproteins (beta Lipoproteins)IBA 10/2006
1	Malondialdehyde (Propanedial)IBA 10/2006
1	LDL Receptors (LDL Receptor)IBA 10/2006
1	BCG Vaccine FDA Link 09/2004
1	Trypsin InhibitorsIBA 07/2002
1	Interferon-gamma (Interferon, gamma)IBA 07/2002
1	Tuberculin (PPD)IBA 03/2001
1	lipoarabinomannan (LAM)IBA 03/2001
1	Endoplasmic Reticulum Chaperone BiPIBA 02/2001
1	pristane (pristan)IBA 02/2001
1	CollagenIBA 02/2001
1	AutoantigensIBA 02/2001
1	Collagen Type II (Type II Collagen)IBA 02/2001
1	AllergensIBA 01/2000
1	Immunodominant EpitopesIBA 01/2000
1	Interleukin-5 (Interleukin 5)IBA 01/2000
1	Interleukin-4 (Interleukin 4)IBA 01/2000

Therapy/Procedure

3	Oral Administration 10/2006 - 12/2000
2	Immunotherapy 12/2000 - 01/2000
1	Therapeutics 10/2006
1	Intranasal Administration 03/2000